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Science · 2026-11-05
Scientists reveal how cosignaling receptors dually regulate T cell activation via phase separation
Previous studies have shown that upon antigen stimulation, the T cell receptor (TCR) undergoes phase separation with the kinase Lck to mediate rapid T cell activation. However, the manner in which costimulating receptors regulate this process has remained unclear.
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Original source: Phys.org Research ↗
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